Food Chain Borne Effect of Cadmium and Cyanide on Some Biochemical Indices in the Liver of Rats

Diverse organismsuch as mammals and fishes exposure to noxious waste in the surroundings is a continuous routine active absorption propagation of contaminants humans through food chain. In order determine level toxicity across chain,this research was structured identify some biochemical alterations hepatic tissue rats fed cadmium, cyanide mixture cadmium contaminated catfish diet. Fish were assigned into four groups exposed both toxicants (cadmium cyanide) single combined states. Each toxicant administered chloride (CdCl2) potassium (KCN) on dose 0.4 mg toxicant/100 ml water for about weeks 100 Liter capacity plastic aquarium. group A housed uncontaminated (control), B cyanide-contaminated water, C washoused cadmium-contaminated D + water. Subsequently fish sacrificed, dried served protein source prepared diet used feed rats. The also allocated 28 days.Thereafter they sacrificed liver excised assays. end result attained specified that consumption changed exploits enzymes; alanine aminotransferase (ALT) aspartate (AST) alkaline phosphatase (ALP) lactate dehydrogenase (LDH) serum notable decrease (P<0.05) detected albumin, total globulin experimental Also, significant increase/decrease oxidative stress parameterswas noted tissues Thus, discoveries stipulated interaction with via food-chain led anomaly function so perturbing usual metabolic actions.